SCHEMBL28866770

SCHEMBL28866770

NSCc1ccc(N)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 3/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
GFER P55789 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
MAPT P10636 1/20 0.44
MAOB P27338 4/20 0.44
MAOA P21397 2/20 0.44
NOS1 P29475 1/20 0.44
MAPK1 P28482 1/20 0.39
TP53 P04637 1/20 0.38
CYP19A1 P11511 1/20 0.38
IDO1 P14902 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3241999 0.80 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRTDP1GFER
SCHEMBL3244307 0.80 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRTDP1GFER
SCHEMBL9976791 0.76 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRTDP1GFER
SCHEMBL514208 0.76 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRTDP1GFER
SCHEMBL14081380 0.76 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRTDP1GFER
SCHEMBL23891977 0.76 IDO1 (0.56) ALDH1A1TSHRTDP1NOS1MAPK1
SCHEMBL23177886 0.76 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRTDP1GFER
SCHEMBL20343989 0.76 ABAT (0.52) ALDH1A1CYP3A4TDP1MEN1KMT2A
SCHEMBL2468970 0.76 IDO1 (0.56) ALDH1A1TDP1RAB9AIDO1
SCHEMBL514209 0.76 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRTDP1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115219644-A By means of H 2 Activity evaluation device and method for S-prepared aryl thioamide catalyst 福州大学 2022-10-21 CN disclosed