SCHEMBL28867348

SCHEMBL28867348

CCC[Si](Cl)(C(C)C)C(C)C.N#CC#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26000148 0.87
SCHEMBL27546422 0.74 MCL1 (0.30)
SCHEMBL2269899 0.73
SCHEMBL715622 0.73
SCHEMBL28302407 0.72
SCHEMBL4644804 0.72 TSHR (0.32)
SCHEMBL523935 0.71 TSHR (0.40)
SCHEMBL1555672 0.68 TSHR (0.40)
SCHEMBL523489 0.68 TSHR (0.40)
SCHEMBL707345 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109070050-A The porous surface material of the core comprising coating for chromatographic isolation with narrow particle size distribution, preparation method, with and application thereof 沃特世科技公司 2018-12-21 CN disclosed
CN-109070053-A A porous material of controlled porosity for chromatographic separations; a process for the preparation thereof; and uses thereof 沃特世科技公司 2018-12-21 CN disclosed