SCHEMBL28867765

SCHEMBL28867765

C=Cc1ccc(C(O)=S)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 2/20 0.41
TAS1R3 Q7RTX0 3/20 0.37
TAS1R1 Q7RTX1 3/20 0.37
HDAC8 Q9BY41 1/20 0.36
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
TRPA1 O75762 1/20 0.32
HDAC2 Q92769 1/20 0.32
KMT2A Q03164 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
AKT1 P31749 1/20 0.30
PRMT5 O14744 1/20 0.30
PRMT1 Q99873 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL2045958 0.84 ALDH1A1 (0.45) ALDH1A1TSHRTDP1KMT2AHPGD
SCHEMBL25360351 0.82 ALDH1A1 (0.58) ALDH1A1TSHRTDP1TAS1R3TAS1R1
Hydrogen Peroxide SCHEMBL28624206 0.81 ALDH1A1 (0.85) ALDH1A1TSHRTDP1TAS1R3TAS1R1
Thiobenzoic Acid SCHEMBL8082926 0.80 ALDH1A1 (0.41) ALDH1A1TSHRTAS1R3TAS1R1TRPA1
SCHEMBL6897191 0.78 ALDH1A1 (0.52) ALDH1A1TSHRTDP1TAS1R3TAS1R1
SCHEMBL6517873 0.78 ALDH1A1 (0.52) ALDH1A1TSHRTDP1TAS1R3TAS1R1
SCHEMBL10972630 0.78 ALDH1A1 (0.52) ALDH1A1TSHRTDP1TAS1R3TAS1R1
SCHEMBL1178820 0.78 TSHR (0.41) ALDH1A1TSHRKMT2AHPGDHSD17B10
SCHEMBL13826229 0.77 ALDH1A1 (0.58) ALDH1A1TSHRTDP1TAS1R3TAS1R1
SCHEMBL16536 0.75 ALDH1A1 (0.62) ALDH1A1TSHRTDP1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912431-B Chloroprene-unsaturated nitrile copolymer composition and vulcanized molded article 电化株式会社 2023-04-04 CN disclosed
CN-112955503-B Chloroprene rubber composition and vulcanized molded article 电化株式会社 2022-10-21 CN disclosed