SCHEMBL28867923

SCHEMBL28867923

CN(C(=O)c1ccccc1)c1ccc(Br)cc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.59
KMT2A Q03164 1/20 0.59
NR1H3 Q13133 2/20 0.58
NR1H2 P55055 1/20 0.58
HTT P42858 1/20 0.54
EGFR P00533 1/20 0.54
ERBB2 P04626 1/20 0.54
ALDH1A1 P00352 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MAOA P21397 2/20 0.49
ATM Q13315 1/20 0.47
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
HPGD P15428 1/20 0.47
POLB P06746 1/20 0.46
PDE10A Q9Y233 1/20 0.46
KDM1A O60341 1/20 0.46
MAOB P27338 1/20 0.46
SIRT2 Q8IXJ6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28867918 0.93 KMT2A (0.64) KDM4EKMT2ANR1H3NR1H2HTT
SCHEMBL24669260 0.90 KDM4E (0.50) KDM4EKMT2ANR1H3NR1H2HTT
SCHEMBL9001651 0.90 KMT2A (0.69) KDM4EKMT2ANR1H3NR1H2HTT
SCHEMBL24891812 0.87 EGFR (0.49) KDM4EKMT2ANR1H3NR1H2HTT
SCHEMBL493114 0.86 KMT2A (0.75) KDM4EKMT2ANR1H3NR1H2HTT
SCHEMBL24891762 0.84 HSD17B1 (0.50) KDM4EKMT2AHTTEGFRERBB2
SCHEMBL3089099 0.83 KMT2A (0.61) KDM4EKMT2ANR1H3NR1H2HTT
SCHEMBL257815 0.83 KMT2A (0.61) KDM4EKMT2ANR1H3NR1H2HTT
SCHEMBL14410651 0.83 KMT2A (0.61) KDM4EKMT2ANR1H3NR1H2HTT
SCHEMBL9001653 0.82 KMT2A (0.75) KDM4EKMT2ANR1H3NR1H2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115057794-B Method for removing methylation of cerium catalytic oxidation amide by visible light induction 桂林理工大学 2023-11-17 CN disclosed
CN-115057794-A Novel method for removing methylation of cerium-induced catalytic oxidation amide by visible light 桂林理工大学 2022-09-16 CN disclosed