SCHEMBL28868017

SCHEMBL28868017

Cc1ccc(C(C)NS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
POLB P06746 1/20 0.56
CNR1 P21554 2/20 0.53
CA12 O43570 4/20 0.50
CA9 Q16790 4/20 0.50
CA2 P00918 4/20 0.50
MMP2 P08253 3/20 0.50
CA14 Q9ULX7 2/20 0.50
CA1 P00915 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KCNA5 P22460 1/20 0.49
TSHR P16473 1/20 0.49
CA7 P43166 2/20 0.48
MMP1 P03956 1/20 0.48
MMP3 P08254 1/20 0.48
MMP7 P09237 1/20 0.48
MMP9 P14780 1/20 0.48
MMP13 P45452 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28427228 1.00 ALDH1A1 (0.60) ALDH1A1POLBCNR1CA12CA9
SCHEMBL14619788 0.93 ALDH1A1 (0.69) ALDH1A1POLBCNR1CA12CA9
SCHEMBL28423968 0.93 ALDH1A1 (0.69) ALDH1A1POLBCNR1CA12CA9
SCHEMBL29259803 0.91 CNR1 (0.60) ALDH1A1POLBCNR1CA12CA9
SCHEMBL29222887 0.91 ALDH1A1 (0.58) ALDH1A1POLBCNR1CA12CA9
SCHEMBL3759433 0.89 ALDH1A1 (0.73) ALDH1A1POLBCNR1CA12CA9
SCHEMBL28426090 0.89 ALDH1A1 (0.73) ALDH1A1POLBCNR1CA12CA9
Hydrochloric Acid SCHEMBL8123779 0.87 ALDH1A1 (0.71) ALDH1A1POLBCNR1CA12CA9
SCHEMBL29222859 0.86 ALDH1A1 (0.60) ALDH1A1POLBCNR1CA12CA9
SCHEMBL28420194 0.83 CNR1 (0.54) ALDH1A1CNR1CA12CA9CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108976178-A A kind of preparation method of chiral sulfonamide class organic compound 云南民族大学 2018-12-11 CN disclosed