SCHEMBL28868029

SCHEMBL28868029

CC(C)(C)OC(=O)NCCOCCOCCOC(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.52
LMNA P02545 2/20 0.49
HTR1A P08908 3/20 0.48
ADRB2 P07550 2/20 0.48
TDP1 Q9NUW8 2/20 0.46
BCHE P06276 1/20 0.46
CNR2 P34972 1/20 0.46
CYP2D6 P10635 1/20 0.45
SCN1A P35498 1/20 0.45
SLC6A3 Q01959 1/20 0.45
SCN5A Q14524 1/20 0.45
SCN2A Q99250 1/20 0.45
SCN3A Q9NY46 1/20 0.45
SYK P43405 1/20 0.44
SERPINE1 P05121 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8457758 0.92 IDO1 (0.62) IDO1SMN1; SMN2LMNAHTR1AADRB2
SCHEMBL21113585 0.86 SMN1; SMN2 (0.72) IDO1SMN1; SMN2LMNAHTR1AADRB2
SCHEMBL24064580 0.86 L3MBTL1 (0.52) SMN1; SMN2LMNATDP1MAPT
SCHEMBL20590258 0.84 TDP1 (0.58) IDO1LMNATDP1CA12CA1
SCHEMBL21070510 0.82 SMN1; SMN2 (0.64) IDO1SMN1; SMN2LMNABCHECNR2
SCHEMBL12672212 0.82 SMN1; SMN2 (0.65) IDO1SMN1; SMN2LMNABCHECNR2
SCHEMBL12196470 0.82 SMN1; SMN2 (0.76) IDO1SMN1; SMN2LMNABCHECNR2
SCHEMBL16906832 0.81 BCHE (0.61) IDO1SMN1; SMN2HTR1AADRB2BCHE
SCHEMBL23447193 0.81 IDO1 (0.53) IDO1SMN1; SMN2LMNAHTR1AADRB2
SCHEMBL23886965 0.81 IDO1 (0.53) IDO1SMN1; SMN2LMNAHTR1AADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115246799-A Compound, preparation method thereof and nano photothermal reagent containing compound 温州医科大学 2022-10-28 CN disclosed