Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543513 | 0.93 | TSHR (0.55) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL19925 | 0.90 | SLC22A6 (0.65) | TSHRSLC22A6CAMK2ALMNANFKB1 | |
| SCHEMBL1289888 | 0.90 | SLC22A6 (0.65) | TSHRSLC22A6CAMK2ALMNANFKB1 | |
| Ammonia Solution, Strong SCHEMBL8041259 | 0.87 | SLC22A6 (0.61) | TSHRSLC22A6CAMK2ALMNANFKB1 | |
| SCHEMBL28929949 | 0.87 | LMNA (0.61) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL2995384 | 0.87 | LMNA (0.61) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL8581028 | 0.87 | LMNA (0.61) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL7218527 | 0.87 | LMNA (0.61) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL1602470 | 0.87 | SLC22A6 (0.61) | TSHRSLC22A6CAMK2ALMNANFKB1 | |
| SCHEMBL10453763 | 0.85 | TSHR (0.63) | TSHRSLC22A6LMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215886-A | Compounds and compositions as endosomal Toll-like receptor inhibitors | 诺华股份有限公司 | 2022-10-21 | — | — | CN | disclosed |