Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26749678 | 0.87 | KMT2A (0.48) | HTTHPGDKMT2AALDH1A1MAPT | |
| SCHEMBL5842514 | 0.85 | POLB (0.59) | HPGDKMT2AALDH1A1MAPTPOLB | |
| SCHEMBL2584802 | 0.84 | HTT (0.50) | HTTHPGDKMT2AALDH1A1MAPT | |
| SCHEMBL6873772 | 0.84 | HTT (0.63) | HTTKMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL29043470 | 0.80 | HDAC3 (0.56) | HTTKMT2AALDH1A1TPSAB1CYP2C19 | |
| SCHEMBL7449318 | 0.80 | POLB (0.54) | HPGDKMT2AALDH1A1MAPTPOLB | |
| SCHEMBL2579036 | 0.79 | HTT (0.49) | HTTHPGDKMT2AALDH1A1MAPT | |
| SCHEMBL2579038 | 0.79 | HTT (0.49) | HTTHPGDKMT2AALDH1A1MAPT | |
| SCHEMBL1907957 | 0.78 | MAPK8 (0.52) | KMT2AALDH1A1POLBCNR2MEN1 | |
| SCHEMBL8802561 | 0.78 | L3MBTL1 (0.48) | HTTKMT2AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020846-A | O- replaces tyrosine Bcl-2 protein inhibitor and preparation method and application | 山东大学 | 2018-12-18 | — | — | CN | disclosed |