Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.51 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1887799 | 0.80 | CYP1A2 (0.49) | MAPTPIM1PIM2NPC1ALDH1A1 | |
| SCHEMBL1887801 | 0.80 | CYP1A2 (0.49) | MAPTPIM1PIM2NPC1ALDH1A1 | |
| SCHEMBL27909084 | 0.78 | MAPT (0.55) | MAPTLMNAPLIN1GAAMAPK1 | |
| SCHEMBL28271227 | 0.78 | MAPT (0.55) | MAPTLMNAPLIN1GAAMAPK1 | |
| SCHEMBL1889059 | 0.78 | EGFR (0.50) | MAPTMAPK1PIM1PIM2NPC1 | |
| SCHEMBL1889060 | 0.78 | EGFR (0.50) | MAPTMAPK1PIM1PIM2NPC1 | |
| Hydrochloric Acid SCHEMBL29288159 | 0.77 | MAPT (0.54) | MAPTLMNAPLIN1GAAMAPK1 | |
| SCHEMBL28434318 | 0.77 | LMNA (0.60) | MAPTLMNAPLIN1GAAMAPK1 | |
| SCHEMBL8911721 | 0.76 | CYP1A2 (0.45) | MAPTPIM1PIM2NPC1ALDH1A1 | |
| SCHEMBL1890697 | 0.74 | CYP1A2 (0.44) | MAPTLMNAGAATDP1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109078014-A | 3,4- dimethoxybenzyliden piperidines keto analog is preparing the application in anti-lung-cancer medicament | 温州医科大学 | 2018-12-25 | — | — | CN | disclosed |