Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28950553 | 0.86 | MAPT (0.47) | HSD17B1VCPMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL24808421 | 0.81 | VCP (0.74) | VCPMAPTSMN1; SMN2NPSR1APP | |
| SCHEMBL400497 | 0.80 | MAPT (0.59) | VCPMAPTSMN1; SMN2MAOBAPP | |
| SCHEMBL6653836 | 0.80 | APP (0.53) | NPSR1APPFFAR1ESR1 | |
| SCHEMBL68968 | 0.80 | NPSR1 (0.59) | VCPMAPTNPSR1APPALDH1A1 | |
| Benzene SCHEMBL28174766 | 0.80 | NPSR1 (0.59) | VCPMAPTNPSR1APPALDH1A1 | |
| SCHEMBL13077427 | 0.79 | VCP (0.71) | VCPMAPTSMN1; SMN2NPSR1MAOB | |
| Lithium SCHEMBL30940463 | 0.78 | APP (0.52) | NPSR1APPFFAR1 | |
| SCHEMBL30940455 | 0.78 | APP (0.52) | NPSR1APPFFAR1 | |
| Potassium SCHEMBL30940461 | 0.78 | APP (0.52) | NPSR1APPFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384715-B | A kind of bromo- 4- phenyl coumarin series compound preparation method of 3- of 7- substitution | 嘉兴学院 | 2019-01-18 | — | — | CN | disclosed |