Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28272465 | 0.99 | OPRM1 (0.59) | OPRM1CYP2D6OPRD1OPRK1KCNH2 | |
| SCHEMBL28270858 | 0.88 | OPRM1 (0.61) | OPRM1CYP2D6OPRD1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL28272360 | 0.87 | OPRM1 (0.61) | OPRM1CYP2D6OPRD1OPRK1KCNH2 | |
| SCHEMBL28270851 | 0.85 | OPRM1 (0.59) | OPRM1CYP2D6OPRD1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL28271016 | 0.85 | OPRM1 (0.58) | OPRM1CYP2D6OPRD1OPRK1KCNH2 | |
| SCHEMBL28272343 | 0.84 | OPRM1 (0.57) | OPRM1CYP2D6OPRD1OPRK1KCNH2 | |
| SCHEMBL28272325 | 0.82 | OPRM1 (0.70) | OPRM1CYP2D6OPRD1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL28270982 | 0.81 | OPRM1 (0.69) | OPRM1CYP2D6OPRD1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL28270867 | 0.81 | OPRM1 (0.69) | OPRM1CYP2D6OPRD1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL28270870 | 0.81 | OPRM1 (0.69) | OPRM1CYP2D6OPRD1OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206417-B | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115124520-A | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-109206417-A | Opioid receptor agonists and uses thereof | 四川海思科制药有限公司 | 2019-01-15 | — | — | CN | disclosed |