Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.74 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.74 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.55 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.53 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.47 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.46 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL27997070 | 1.00 | LPAR1 (0.74) | LPAR1LPAR3LPAR2LPAR5P2RY10 | |
| Serine SCHEMBL27750376 | 0.99 | LPAR1 (0.71) | LPAR1LPAR3LPAR2LPAR5P2RY10 | |
| Serine SCHEMBL27966438 | 0.94 | LPAR1 (0.66) | LPAR1LPAR3LPAR2LPAR5P2RY10 | |
| Serine SCHEMBL27927630 | 0.89 | LPAR1 (0.57) | LPAR1LPAR3LPAR2LPAR5P2RY10 | |
| Serine SCHEMBL28049071 | 0.89 | LPAR1 (0.57) | LPAR1LPAR3LPAR2LPAR5P2RY10 | |
| Dexfosfoserine SCHEMBL28615331 | 0.89 | LPAR1 (0.64) | LPAR1LPAR3LPAR2LPAR5P2RY10 | |
| Serine SCHEMBL28305481 | 0.87 | LPAR5 (0.73) | LPAR1LPAR3LPAR2LPAR5P2RY10 | |
| Alcohol SCHEMBL27915917 | 0.86 | LPAR3 (0.94) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL10896195 | 0.86 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL2814732 | 0.86 | LPAR3 (1.00) | LPAR1LPAR3LPAR2LPAR5LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415723-A | IMPROVED PROMOTERS AND COMPOSITIONS | 牛津大学创新有限公司 | 2019-03-01 | — | — | CN | disclosed |