SCHEMBL28869172

SCHEMBL28869172

CC(c1cncnc1)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.34
DEGS1 O15121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28869171 1.00 CYP19A1 (0.34) CYP19A1DEGS1
SCHEMBL24684602 0.81 DEGS1 (0.33) DEGS1
SCHEMBL18467498 0.78 CYP19A1 (0.35) CYP19A1
SCHEMBL16173922 0.74 CFTR (0.48) CYP19A1
SCHEMBL31463853 0.74 CFTR (0.48) CYP19A1
SCHEMBL19014420 0.74 CFTR (0.48) CYP19A1
SCHEMBL16173921 0.74 CFTR (0.48) CYP19A1
SCHEMBL14762145 0.71 CYP11B2 (0.35) CYP19A1
SCHEMBL2336440 0.71 CYP3A4 (0.43) CYP19A1DEGS1
SCHEMBL31292528 0.71 DEGS1 (0.32) DEGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311887-A Pyrazolo [1,5-a] pyrimidine radicals benzamide compound and they treatment medical conditions in purposes 溶酶体治疗股份有限公司 2019-02-05 CN disclosed