SCHEMBL28869414

SCHEMBL28869414

NC(=O)Cl.O=c1cccc[nH]1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FKBP5 Q13451 1/20 0.70
NOTUM Q6P988 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
CSNK1A1 P48729 1/20 0.36
TYRO3 Q06418 1/20 0.36
DYRK1B Q9Y463 1/20 0.36
DAO P14920 1/20 0.35
AURKA O14965 1/20 0.35
AURKB Q96GD4 1/20 0.35
INCENP Q9NQS7 1/20 0.35
MAPT P10636 2/20 0.34
POLB P06746 1/20 0.34
CYP3A4 P08684 1/20 0.34
PARP1 P09874 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetamide SCHEMBL7526547 0.87 FKBP5 (0.70) FKBP5NOTUMNAPRTCSNK1A1TYRO3
SCHEMBL9596 0.83
SCHEMBL27324502 0.83 FKBP5 (1.00) FKBP5NOTUMNAPRTDAOAURKA
Acetone SCHEMBL27901178 0.82 FKBP5 (0.76) FKBP5NOTUMNAPRTDAOAURKA
SCHEMBL692817 0.81
Methyl Alcohol SCHEMBL28775298 0.81
SCHEMBL10465472 0.81
SCHEMBL25414048 0.81
SCHEMBL1149107 0.81
Water SCHEMBL14333714 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415307-A The manufacturing method of pentamethylene diisocyanate 三井化学株式会社 2019-03-01 CN disclosed