Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 4/20 | 0.46 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16511611 | 1.00 | LMNA (0.58) | LMNANPSR1USP30NPC1MEN1 | |
| SCHEMBL16498824 | 0.84 | HTT (0.44) | LMNANPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2367182 | 0.84 | LMNA (0.63) | LMNANPSR1USP30NPC1MEN1 | |
| SCHEMBL2367183 | 0.84 | LMNA (0.63) | LMNANPSR1USP30NPC1MEN1 | |
| SCHEMBL2409650 | 0.83 | CYP1A2 (0.49) | LMNANPSR1USP30HDAC8POLB | |
| SCHEMBL12567167 | 0.83 | NPC1 (0.58) | LMNANPSR1USP30NPC1MEN1 | |
| SCHEMBL12098332 | 0.82 | LMNA (0.63) | LMNANPSR1USP30NPC1MEN1 | |
| SCHEMBL38657837 | 0.82 | LMNA (0.63) | LMNANPSR1USP30NPC1MEN1 | |
| SCHEMBL30412218 | 0.82 | LMNA (0.60) | LMNANPSR1USP30NPC1MEN1 | |
| SCHEMBL7609243 | 0.82 | LMNA (0.63) | LMNANPSR1USP30NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725365-B | Hepatitis C virus inhibitors and its application | 南京圣和药业股份有限公司 | 2019-02-26 | — | — | CN | disclosed |