Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 8/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28869623 | 0.91 | TP53 (0.52) | TP53MAOBLMNATDP1 | |
| SCHEMBL28869625 | 0.83 | TP53 (0.52) | TP53MAOBLMNATDP1 | |
| SCHEMBL30098366 | 0.83 | TP53 (0.67) | TP53MAOBLMNATDP1 | |
| SCHEMBL30098384 | 0.77 | TP53 (0.60) | TP53MAOBTDP1 | |
| SCHEMBL28869579 | 0.76 | TP53 (0.48) | TP53MAOBLMNAMAPTTDP1 | |
| SCHEMBL30098374 | 0.75 | TP53 (0.73) | TP53MAPTTDP1 | |
| SCHEMBL30098385 | 0.73 | TP53 (0.64) | TP53MAOBMAPTTDP1 | |
| SCHEMBL30098365 | 0.71 | TP53 (0.70) | TP53MAOBMAPT | |
| SCHEMBL30098399 | 0.71 | HPGD (0.65) | TP53LMNA | |
| SCHEMBL5358064 | 0.70 | LMNA (0.57) | TP53LMNAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093389-A | 6-amide chroman-3-formamide derivative and preparation method and application thereof | 广州医科大学 | 2022-09-23 | — | — | CN | disclosed |