Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15034386 | 0.84 | GPR119 (0.53) | HDAC1GPR119PARP1HSD11B1MAPK8 | |
| SCHEMBL31048020 | 0.83 | MEN1 (0.45) | HDAC1GPR119PARP1PARP2HSD11B1 | |
| SCHEMBL30316252 | 0.83 | HDAC1 (0.53) | HDAC1GPR119PARP1HSD11B1MAPK8 | |
| SCHEMBL15249213 | 0.83 | HDAC1 (0.53) | HDAC1GPR119PARP1HSD11B1MAPK8 | |
| SCHEMBL29437386 | 0.83 | HDAC1 (0.53) | HDAC1GPR119PARP1HSD11B1MAPK8 | |
| SCHEMBL18573301 | 0.83 | HDAC1 (0.53) | HDAC1GPR119PARP1HSD11B1MAPK8 | |
| SCHEMBL12425412 | 0.83 | HDAC1 (0.53) | HDAC1GPR119PARP1HSD11B1MAPK8 | |
| SCHEMBL31106310 | 0.83 | HDAC1 (0.53) | HDAC1GPR119PARP1HSD11B1MAPK8 | |
| SCHEMBL22387840 | 0.83 | HDAC1 (0.53) | HDAC1GPR119PARP1HSD11B1MAPK8 | |
| SCHEMBL31459152 | 0.82 | GPR119 (0.52) | HDAC1GPR119PARP1HSD11B1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232121-B | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-115232121-A | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2022-10-25 | — | — | CN | disclosed |