Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.43 |
| ▸ | FABP1 | P07148 | 2/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306430 | 0.86 | NR1H4 (0.52) | NR1H4FABP1HSD17B13 | |
| SCHEMBL19689533 | 0.80 | NR1H4 (0.44) | NR1H4FABP1HSD17B13 | |
| SCHEMBL28320904 | 0.78 | NR1H4 (0.46) | NR1H4FABP1HSD17B13 | |
| SCHEMBL19689512 | 0.78 | NR1H4 (0.46) | NR1H4FABP1HSD17B13 | |
| SCHEMBL27732988 | 0.75 | FFAR4 (0.39) | NR1H4FABP1HSD17B13 | |
| SCHEMBL19705737 | 0.75 | NR1H4 (0.47) | NR1H4FABP1HSD17B13 | |
| SCHEMBL26965107 | 0.74 | NR1H4 (0.59) | NR1H4FABP1HSD17B13 | |
| SCHEMBL24565512 | 0.73 | NR1H4 (0.46) | NR1H4FABP1HSD17B13 | |
| SCHEMBL28242351 | 0.72 | NR1H4 (0.47) | NR1H4FABP1 | |
| SCHEMBL22705335 | 0.72 | NR1H4 (0.43) | NR1H4FABP1HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476636-A | Compounds that modulate FXR (NR1H4) | 吉利德科学公司 | 2019-03-15 | — | — | CN | disclosed |