SCHEMBL28870539

SCHEMBL28870539

CC(C)C(NC(=O)OCc1ccccc1)C(=O)OCCCC(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSB P07858 4/20 0.53
CTSL P07711 4/20 0.53
CTSK P43235 3/20 0.53
CTSS P25774 3/20 0.53
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CAPN1 P07384 1/20 0.49
CASP1 P29466 2/20 0.49
ELANE P08246 2/20 0.48
PRTN3 P24158 1/20 0.48
ATM Q13315 1/20 0.48
CTSD P07339 1/20 0.48
CASP3 P42574 2/20 0.47
CA2 P00918 1/20 0.47
CA5A P35218 1/20 0.47
CASP7 P55210 1/20 0.47
CASP6 P55212 1/20 0.47
CASP8 Q14790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23567826 1.00 CTSB (0.53) CTSBCTSLCTSKCTSSMEN1
SCHEMBL21074164 0.94 CTSB (0.47) CTSBCTSLCTSKCTSSMEN1
SCHEMBL18669035 0.94 CTSB (0.47) CTSBCTSLCTSKCTSSMEN1
SCHEMBL3729516 0.93 CTSB (0.49) CTSBCTSLCTSKCTSSMEN1
SCHEMBL3736830 0.93 CTSB (0.49) CTSBCTSLCTSKCTSSMEN1
SCHEMBL3727406 0.91 CTSB (0.54) CTSBCTSLCTSKCTSSMEN1
SCHEMBL23535950 0.91 CTSB (0.54) CTSBCTSLCTSKCTSSMEN1
SCHEMBL24131773 0.90 CTSB (0.48) CTSBCTSLCTSKCTSSMEN1
SCHEMBL3736788 0.90 SYK (0.50) CTSBCTSLCTSKCTSSMEN1
SCHEMBL24131772 0.90 CTSB (0.48) CTSBCTSLCTSKCTSSMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115244028-A Synthetic method of 4-valyloxy butyric acid 凯瑞康宁生物工程有限公司 2022-10-25 CN disclosed