Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.47 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44226 | 0.87 | CES1 (0.52) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL2581571 | 0.85 | NAPRT (0.58) | KMT2AMEN1ALDH1A1PLOD2PLOD3 | |
| SCHEMBL9419356 | 0.84 | CES1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL9419398 | 0.84 | TDP1 (0.52) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| Methane SCHEMBL10707942 | 0.84 | CES1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL9419372 | 0.84 | CES1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL9419363 | 0.84 | CES1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL9419391 | 0.84 | CES1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL28968164 | 0.84 | CES1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL28159752 | 0.84 | CES1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244043-A | Benzimidazolonyl cinnamamide derivative as TRPV1 antagonist and pharmaceutical composition for treating or preventing pain containing the same as active ingredient | 杰迈肯有限公司 | 2022-10-25 | — | — | CN | disclosed |