Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.47 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7439433 | 0.98 | NAPRT (0.56) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| Pyridine SCHEMBL28870562 | 0.85 | KMT2A (0.52) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL12970081 | 0.83 | NAPRT (0.50) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL713716 | 0.82 | TSHR (0.47) | NAPRTALDH1A1HPGDHTTHSD17B10 | |
| SCHEMBL2817706 | 0.79 | NAPRT (0.50) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10910929 | 0.79 | NAPRT (0.50) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL28774639 | 0.79 | NAPRT (0.50) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL44226 | 0.77 | CES1 (0.52) | NAPRTKMT2AMEN1ALDH1A1CYP3A4 | |
| Isonicotinic Acid SCHEMBL11898509 | 0.76 | NAPRT (0.71) | NAPRTKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL9419372 | 0.75 | CES1 (0.50) | NAPRTKMT2AMEN1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591295-A | Pyridine salt-containing N- (indoleacyl) -N' - (substituted) propyl hydrazide derivative, and preparation method and application thereof | 贵州大学 | 2022-06-07 | — | — | CN | claimed |
| CN-103772576-B | A kind of preparation method being applied to the sorbent material that pristinamycin is separated | WANG JINMING (CN) | 2016-03-09 | — | — | CN | claimed |
| CN-103772576-A | Preparation method of adsorbing agent applied to pristinamycin separation | WANG JINMING | 2014-05-07 | — | — | CN | claimed |
| CN-114702506-B | 11-carbonyl-20-ethoxy source oridonin and 14-OH esterified serial derivatives and application thereof | 郑州大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-110386919-B | Nuclear transport modulators and uses thereof | 卡尔约药物治疗公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-110183422-B | Nuclear transport modulators and uses thereof | 卡尔约药物治疗公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-113845557-B | Tripterine pyridine acrylic acid derivative and preparation method and medical application thereof | 中国药科大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-114702506-A | 11-carbonyl-20-ethoxy economic oridonin and 14-OH esterified series derivatives and application thereof | 郑州大学 | 2022-07-05 | — | — | CN | disclosed |
| EP-3710439-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2020-09-23 | — | — | EP | disclosed |
| CN-110386919-A | Nuclear translocation regulator and application thereof | 卡尔约药物治疗公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110183422-A | Nuclear translocation regulator and application thereof | 卡尔约药物治疗公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-1136213-C | New benzothiophene, benzofuran and indole compounds, preparation method therefor and medicine composition containing same | ɪά��ʵ���� | 2004-01-28 | — | — | CN | disclosed |
| US-6444694-B1 | ANTIPROLIFERATIVE AGENTS | WYETH | 2002-09-03 | — | — | US | disclosed |
| EP-0830345-B1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PROD (US) | 2001-09-05 | — | — | EP | disclosed |
| CN-1293192-A | New benzothiophene, benzofuran and indole compounds, preparation method therefor and medicine composition containing same | ADIR (FR) | 2001-05-02 | — | — | CN | disclosed |
| EP-0830345-A1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-25 | — | — | EP | disclosed |
| US-5612336-A | Heterocyclic amide derivatives as tachykinin antagonists | MERCK, SHARP & DOHME LTD. (GB) | 1997-03-18 | — | — | US | disclosed |
| WO-1996039391-A1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |
| WO-1994001402-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS TACHYKININ DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1994-01-20 | — | — | WO | disclosed |
| EP-0074229-A1 | Triazole gastric anti-secretory agents | PFIZER INC. (US) | 1983-03-16 | — | — | EP | disclosed |