Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8327649 | 1.00 | TSHR (0.74) | TSHRMEN1KMT2ATHRBHTT | |
| Triethylene Glycol SCHEMBL275016 | 1.00 | TSHR (0.74) | TSHRMEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL2516099 | 1.00 | TSHR (0.74) | TSHRMEN1KMT2ATHRBHTT | |
| Di(Hydroxyethyl)Ether SCHEMBL4453213 | 0.98 | TSHR (0.77) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL587577 | 0.98 | TSHR (0.77) | TSHRMEN1KMT2ATHRBHTT | |
| Triethylene Glycol SCHEMBL19064944 | 0.94 | MEN1 (0.76) | TSHRMEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL28282676 | 0.94 | MEN1 (0.76) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL26126895 | 0.92 | TSHR (0.68) | TSHRMEN1KMT2ATHRBHTT | |
| Triethylene Glycol SCHEMBL19064978 | 0.92 | MEN1 (0.80) | TSHRMEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL28282561 | 0.91 | MEN1 (0.72) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109642107-A | Non-aqueous composition for ink | 阪田油墨股份有限公司 | 2019-04-16 | — | — | CN | disclosed |