Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942798 | 1.00 | DGKA (0.61) | DGKAMAPTALDH1A1THRBCNR1 | |
| SCHEMBL19402727 | 0.88 | DGKA (0.77) | DGKAMAPTALDH1A1THRBCNR1 | |
| SCHEMBL19376381 | 0.88 | DGKA (0.77) | DGKAMAPTALDH1A1THRBCNR1 | |
| SCHEMBL5933172 | 0.88 | DGKA (0.77) | DGKAMAPTALDH1A1THRBCNR1 | |
| SCHEMBL3338674 | 0.88 | DGKA (0.77) | DGKAMAPTALDH1A1THRBCNR1 | |
| SCHEMBL10346903 | 0.88 | DGKA (0.77) | DGKAMAPTALDH1A1THRBCNR1 | |
| SCHEMBL974095 | 0.88 | DGKA (0.77) | DGKAMAPTALDH1A1THRBCNR1 | |
| SCHEMBL19397840 | 0.88 | DGKA (0.77) | DGKAMAPTALDH1A1THRBCNR1 | |
| SCHEMBL973787 | 0.88 | DGKA (0.77) | DGKAMAPTALDH1A1THRBCNR1 | |
| SCHEMBL2678233 | 0.88 | DGKA (0.77) | DGKAMAPTALDH1A1THRBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115074467-A | Leather tanning process, anionic active agent composition, use of cationic active agents for the pre-tanning of leather and tanned leather | 施华团队股份公司 | 2022-09-20 | — | — | CN | disclosed |