Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.55 |
| ▸ | CCND1 | P24385 | 3/20 | 0.55 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28870804 | 1.00 | CDK4 (0.55) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL29954579 | 0.80 | CDK4 (0.48) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL10442856 | 0.80 | CDK4 (0.48) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL10442857 | 0.80 | CDK4 (0.48) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5820790 | 0.80 | CDK4 (0.70) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL97837 | 0.79 | CDK4 (0.57) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL359233 | 0.79 | ERN1 (0.61) | ALDH1A1ERN1MAPTCD38MEN1 | |
| SCHEMBL629076 | 0.79 | CDK4 (0.57) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL29952063 | 0.79 | ERN1 (0.61) | ALDH1A1ERN1MAPTCD38MEN1 | |
| SCHEMBL30794071 | 0.78 | ERN1 (0.59) | ALDH1A1ERN1MAPTCD38MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092769-B | Chromene derivative and synthesis method and application thereof | 华东师范大学 | 2022-09-20 | — | — | CN | claimed |
| CN-110092769-B | Chromene derivative and synthesis method and application thereof | 华东师范大学 | 2022-09-20 | — | — | CN | disclosed |