SCHEMBL629076

SCHEMBL629076

O=C/C=C/c1ccccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 2/20 0.57
CCND1 P24385 2/20 0.57
HDAC1 Q13547 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
GSR P00390 1/20 0.48
ALDH1A1 P00352 3/20 0.48
LMNA P02545 2/20 0.48
MAPK1 P28482 2/20 0.48
TRPA1 O75762 1/20 0.48
ALOX5 P09917 1/20 0.48
CCNB2 O95067 1/20 0.46
CDK1 P06493 1/20 0.46
CCNB1 P14635 1/20 0.46
CCNB3 Q8WWL7 1/20 0.46
MAPT P10636 5/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL97837 1.00 CDK4 (0.57) CDK4CCND1HDAC1HDAC8HDAC6
SCHEMBL11461138 0.85 ALDH1A1 (0.56) HDAC1HDAC8HDAC6GSRALDH1A1
SCHEMBL10137939 0.83 ALDH1A1 (0.54) HDAC1HDAC8HDAC6GSRALDH1A1
SCHEMBL16476616 0.83 CDK4 (0.70) CDK4CCND1ALDH1A1LMNAMAPK1
SCHEMBL11070320 0.83 CDK4 (0.70) CDK4CCND1ALDH1A1LMNAMAPK1
SCHEMBL10442857 0.83 CDK4 (0.48) CDK4CCND1HDAC1ALDH1A1LMNA
SCHEMBL10442856 0.83 CDK4 (0.48) CDK4CCND1HDAC1ALDH1A1LMNA
SCHEMBL29954579 0.83 CDK4 (0.48) CDK4CCND1HDAC1ALDH1A1LMNA
SCHEMBL9586694 0.80 ALDH1A1 (0.62) HDAC1HDAC8HDAC6GSRALDH1A1
SCHEMBL1058814 0.80 ALDH1A1 (0.62) HDAC1HDAC8HDAC6GSRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978634-A Flame-retardant corrosion-resistant power cable and preparation method thereof 东莞市君上传导线材有限公司 2025-05-13 CN claimed
CN-119529553-A Smoke-suppressing bird-repelling sand-containing fog sealing layer and preparation method thereof 中国石油化工股份有限公司 2025-02-28 CN claimed
CN-119522906-A Smoke-suppressing bird-repellent microcapsule, smoke-suppressing bird-repellent asphalt additive and preparation method thereof 中国石油化工股份有限公司 2025-02-28 CN claimed
WO-2021259288-A1 AGONIST OF DEACETYLASE AND USE THEREOF 广州中医药大学(广州中医药研究院) 2021-12-30 WO claimed
EP-3791008-A1 CORROSION INHIBITOR WITH IMPROVED PERFORMANCE AT HIGH TEMPERATURES Services Petroliers Schlumberger (FR) 2021-03-17 EP claimed
CN-109627492-B Preparation method and application of antibacterial hydrophobic inorganic-organic hybrid antibacterial agent 浙江工业大学 2020-08-18 CN claimed
WO-2019213740-A1 NOVEL DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH FLUID ENERGY GROUP LTD. (CA) 2019-11-14 WO claimed
CN-106916093-B A kind of method that N-heterocyclic carbine catalyzes and synthesizes polysubstituted pyrrole alkane ketone compounds 福州大学 2019-07-09 CN claimed
CN-107827852-A Pogostone derivative and its production and use 成都中医药大学 2018-03-23 CN claimed
CN-104860841-B 4-chlorocinnamaldehyde aminobutyric acid Schiff base, 4-chlorocinnamaldehyde aminobutyric acid Schiff base salt, and preparation method thereof 广西南宁诺惠生物科技有限公司 2017-03-22 CN claimed
CN-102218091-B Application of cinnamon oil, cinnamyl aldehyde and derivatives of cinnamyl aldehyde in preparation of histamine H3 acceptor antagonist or inverse agonist medicaments CHENGDU MEDICAL COLLEGE 2012-11-07 CN claimed
CN-102746172-A Preparation method of dimethylaminocinnamaldehyde HUBEI YUANCHENG PHARMACEUTICAL 2012-10-24 CN claimed
CN-102669437-A Application of p-chlorocinnamaldehyde serving as animal growth accelerant GUANGZHOU ZHIXIAN FEED ADDITIVES CO LTD 2012-09-19 CN claimed
EP-2125989-B1 IMPROVED CORROSION-INHIBITING ADDITIVES, TREATMENT FLUIDS, AND ASSOCIATED METHODS HALLIBURTON ENERGY SERV INC (US) 2012-09-05 EP claimed
CN-102218091-A Application of cinnamon oil, cinnamyl aldehyde and derivatives of cinnamyl aldehyde in preparation of histamine H3 acceptor antagonist or inverse agonist medicaments CHENGDU MEDICAL COLLEGE 2011-10-19 CN claimed
WO-2008071928-A2 CORROSION INHIBITOR INTENSIFIER COMPOSITIONS AND ASSOCIATED METHODS HALLIBURTON ENERGY SERVICES, INC. (US) 2008-06-19 WO claimed
EP-1689911-A1 METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION Halliburton Energy Services, Inc. (US) 2006-08-16 EP claimed
WO-2005054544-A1 METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION HALLIBURTON ENERGY SERVICES, INC. (US) 2005-06-16 WO claimed
EP-0520336-A2 Aldehyde derivatives and their use as calpain inhibitors FUJIREBIO Inc. (JP) 1992-12-30 EP claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed