Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887176 | 1.00 | TLR3 (0.38) | TLR3ABCC9HIF1ATSHRSIRT2 | |
| SCHEMBL14313878 | 1.00 | TLR3 (0.38) | TLR3ABCC9HIF1ATSHRSIRT2 | |
| SCHEMBL5988483 | 0.82 | ABCC9 (0.40) | ABCC9 | |
| SCHEMBL5988487 | 0.82 | ABCC9 (0.40) | ABCC9 | |
| SCHEMBL10396900 | 0.79 | ABCC9 (0.40) | TLR3ABCC9HIF1ATSHRKMT2A | |
| SCHEMBL10396898 | 0.79 | ABCC9 (0.40) | TLR3ABCC9HIF1ATSHRKMT2A | |
| SCHEMBL10396899 | 0.79 | ABCC9 (0.40) | TLR3ABCC9HIF1ATSHRKMT2A | |
| SCHEMBL2891183 | 0.79 | KCNH2 (0.40) | TLR3ABCC9KMT2AHTTALDH1A1 | |
| SCHEMBL2880124 | 0.79 | KCNH2 (0.40) | TLR3ABCC9KMT2AHTTALDH1A1 | |
| SCHEMBL5990959 | 0.79 | ABCC9 (0.39) | ABCC9KMT2AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718629-B1 | Benzopyran compounds useful for the treatment of arrhytmia | NISSAN CHEMICAL IND LTD (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-7781483-B2 | Benzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-24 | — | — | US | disclosed |