Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.63 |
| ▸ | LCK | P06239 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16226054 | 0.89 | EPHX2 (0.57) | EPHX2LCKMAPTNPC1RAB9A | |
| SCHEMBL4729669 | 0.87 | LCK (0.58) | EPHX2LCKMAPTNPC1RAB9A | |
| SCHEMBL23198991 | 0.85 | EPHX2 (0.65) | EPHX2LCKMAPTNPC1RAB9A | |
| SCHEMBL29871062 | 0.83 | EPHX2 (0.66) | EPHX2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL16932394 | 0.79 | ELANE (0.55) | LCKMAPTNPC1RAB9AMEN1 | |
| SCHEMBL30961641 | 0.79 | ELANE (0.55) | LCKMAPTNPC1RAB9AMEN1 | |
| SCHEMBL30485987 | 0.79 | LCK (0.58) | EPHX2LCKMAPTNPC1RAB9A | |
| SCHEMBL28633685 | 0.78 | ELANE (0.62) | LCKMAPTNPC1RAB9AMEN1 | |
| SCHEMBL27927334 | 0.78 | EPHX2 (0.86) | EPHX2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL31322006 | 0.77 | EPHX2 (1.00) | EPHX2MAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115245533-B | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | claimed |
| CN-115245533-A | Application of south mountain flower root extract in pulmonary fibrosis treatment | 中国医学科学院药物研究所 | 2022-10-28 | — | — | CN | claimed |
| CN-116585295-A | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-08-15 | — | — | CN | disclosed |
| CN-115245533-B | Application of Nanshan flower root extract in treating pulmonary fibrosis | 中国医学科学院药物研究所 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022228095-A1 | APPLICATION OF PRISMATOMERIS CONNATA Y. Z. RUAN ROOT EXTRACT IN PREPARATION OF MEDICINE FOR TREATING PULMONARY FIBROSIS | 中国医学科学院药物研究所 | 2022-11-03 | — | — | WO | disclosed |
| CN-115245533-A | Application of south mountain flower root extract in pulmonary fibrosis treatment | 中国医学科学院药物研究所 | 2022-10-28 | — | — | CN | disclosed |