Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | ACLY | P53396 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 4/20 | 0.47 |
| ▸ | BCL2 | P10415 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872297 | 0.87 | EPHX2 (0.63) | LCKPIM1ACLYMAPTALDH1A1 | |
| SCHEMBL30485987 | 0.86 | LCK (0.58) | LCKPIM1ACLYMAPTALDH1A1 | |
| SCHEMBL18601895 | 0.85 | MAPT (0.65) | LCKPIM1MAPTALDH1A1GLA | |
| SCHEMBL5968251 | 0.83 | BCL2 (0.67) | LCKACLYMAPTALDH1A1ELANE | |
| SCHEMBL26136410 | 0.82 | ELANE (0.57) | LCKPIM1ACLYMAPTALDH1A1 | |
| SCHEMBL16226054 | 0.82 | EPHX2 (0.57) | LCKPIM1MAPTALDH1A1GLA | |
| SCHEMBL31441199 | 0.79 | EPHX2 (0.64) | LCKPIM1MAPTALDH1A1GLA | |
| SCHEMBL24148896 | 0.79 | TTR (0.70) | LCKACLYMAPTALDH1A1THRB | |
| SCHEMBL27796804 | 0.79 | TTR (0.70) | LCKACLYMAPTALDH1A1THRB | |
| SCHEMBL30334888 | 0.78 | ELANE (0.73) | LCKPIM1ACLYMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053481-A1 | MICRONEEDLE ARRAYS | SVIP 6 LLC (US) | 2008-05-08 | — | — | WO | disclosed |