Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872322 | 0.80 | RAB9A (0.50) | EPHX2ACHEMEN1NPC1RAB9A | |
| SCHEMBL23198991 | 0.70 | EPHX2 (0.65) | EPHX2TDP1MEN1NPC1RAB9A | |
| SCHEMBL27927334 | 0.69 | EPHX2 (0.86) | EPHX2CYP1A2CYP2C19MEN1NPC1 | |
| SCHEMBL31322006 | 0.68 | EPHX2 (1.00) | EPHX2CYP1A2CYP2C19CCNB2CDK1 | |
| SCHEMBL29871062 | 0.68 | EPHX2 (0.66) | EPHX2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL16226754 | 0.68 | EPHX2 (1.00) | EPHX2CYP1A2CYP2C19CCNB2CDK1 | |
| SCHEMBL29396060 | 0.68 | EPHX2 (1.00) | EPHX2CYP1A2CYP2C19CCNB2CDK1 | |
| SCHEMBL30637603 | 0.68 | ATM (0.91) | ATMTDP1CYP1A2CYP2C19TARBP2 | |
| SCHEMBL5821723 | 0.67 | EPHX2 (0.57) | EPHX2ATMTDP1CYP1A2CYP2C19 | |
| SCHEMBL29498083 | 0.66 | PIM1 (0.43) | EPHX2CYP1A2CYP2C19CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022228095-A1 | APPLICATION OF PRISMATOMERIS CONNATA Y. Z. RUAN ROOT EXTRACT IN PREPARATION OF MEDICINE FOR TREATING PULMONARY FIBROSIS | 中国医学科学院药物研究所 | 2022-11-03 | — | — | WO | claimed |
| CN-115245533-A | Application of south mountain flower root extract in pulmonary fibrosis treatment | 中国医学科学院药物研究所 | 2022-10-28 | — | — | CN | claimed |
| WO-2022228095-A1 | APPLICATION OF PRISMATOMERIS CONNATA Y. Z. RUAN ROOT EXTRACT IN PREPARATION OF MEDICINE FOR TREATING PULMONARY FIBROSIS | 中国医学科学院药物研究所 | 2022-11-03 | — | — | WO | disclosed |
| CN-115245533-A | Application of south mountain flower root extract in pulmonary fibrosis treatment | 中国医学科学院药物研究所 | 2022-10-28 | — | — | CN | disclosed |