Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290248 | 0.87 | TSHR (0.43) | LMNAHTTGLATSHRL3MBTL1 | |
| SCHEMBL28802249 | 0.82 | LMNA (0.36) | LMNAHTTGLATSHRL3MBTL1 | |
| SCHEMBL1436564 | 0.82 | LMNA (0.36) | LMNAHTTGLATSHRL3MBTL1 | |
| SCHEMBL19765272 | 0.82 | LMNA (0.36) | LMNAHTTGLATSHRL3MBTL1 | |
| SCHEMBL2564843 | 0.82 | LMNA (0.36) | LMNAHTTGLATSHRL3MBTL1 | |
| SCHEMBL26434100 | 0.82 | LMNA (0.36) | LMNAHTTGLATSHRL3MBTL1 | |
| SCHEMBL16335884 | 0.81 | TSHR (0.39) | HTTGLATSHRL3MBTL1LTB4R | |
| SCHEMBL15155150 | 0.81 | TSHR (0.39) | LMNAHTTGLATSHRL3MBTL1 | |
| SCHEMBL22443245 | 0.81 | GLA (0.35) | LMNAHTTGLATSHRL3MBTL1 | |
| SCHEMBL28895929 | 0.81 | GLA (0.35) | LMNAHTTGLATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790079-A | C (the sp of organic zinc reagent and heterocycle (quasi-) halide3)-C(sp2) cross-coupling reaction | 香港科技大学 | 2019-05-21 | — | — | CN | disclosed |