SCHEMBL28873207

SCHEMBL28873207

CCOC(=O)c1nc(-c2ccc(OC)cc2)oc1C(C)(C)C

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 6/20 0.73
PDCD4 Q53EL6 1/20 0.73
POLB P06746 2/20 0.50
IKBKB O14920 1/20 0.50
GAA P10253 1/20 0.50
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 2/20 0.49
KMT2A Q03164 2/20 0.49
HSD17B10 Q99714 1/20 0.49
MAPT P10636 2/20 0.46
GABRA2 P47869 1/20 0.46
GABRB2 P47870 1/20 0.46
HTT P42858 3/20 0.46
MAPK10 P53779 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27843107 0.89 TARBP2 (0.72) TARBP2PDCD4POLBIKBKBGAA
SCHEMBL29162709 0.86 TARBP2 (0.68) TARBP2PDCD4POLBGAAKDM4E
SCHEMBL3535824 0.85 TARBP2 (1.00) TARBP2PDCD4POLBIKBKBGAA
SCHEMBL28297242 0.82 TARBP2 (1.00) TARBP2PDCD4POLBIKBKBGAA
SCHEMBL3539144 0.81 TARBP2 (0.84) TARBP2PDCD4POLBIKBKBGAA
SCHEMBL5192166 0.81 TARBP2 (0.75) TARBP2PDCD4POLBIKBKBGAA
SCHEMBL13771095 0.81 TARBP2 (0.84) TARBP2PDCD4POLBIKBKBGAA
SCHEMBL18003410 0.81 TARBP2 (0.52) TARBP2PDCD4KDM4EALDH1A1HPGD
SCHEMBL28297232 0.81 TARBP2 (0.82) TARBP2PDCD4POLBIKBKBGAA
SCHEMBL3537883 0.81 TARBP2 (0.82) TARBP2PDCD4POLBIKBKBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810071-A A kind of miRNA biosynthesis inhibitor 中国科学院成都生物研究所 2019-05-28 CN disclosed