Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302975 | 0.82 | GRIN1 (0.40) | SLC6A4TACR1GRIN1GRIN2AGRIN2B | |
| SCHEMBL28301555 | 0.74 | OPRM1 (0.41) | SLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL27593274 | 0.64 | GRIN1 (0.46) | SLC6A4SLC6A2SLC6A3CYP2B6GRIN2D | |
| SCHEMBL28303029 | 0.62 | TSHR (0.36) | — | |
| SCHEMBL902318 | 0.61 | SLC6A2 (0.36) | SLC6A4SLC6A2SLC6A3CYP2B6GRIN2D | |
| SCHEMBL1626961 | 0.61 | OPRM1 (0.40) | SLC6A4SLC6A2SLC6A3CYP2B6GRIN2D | |
| SCHEMBL28870944 | 0.61 | OPRM1 (0.37) | SLC6A4SLC6A2SLC6A3CYP2B6GRIN2D | |
| SCHEMBL6450620 | 0.61 | MAPK1 (0.32) | SIGMAR1MAPK1OPRL1 | |
| SCHEMBL14359682 | 0.58 | DPP4 (0.52) | SLC6A4TACR1SLC6A2SLC6A3MEN1 | |
| SCHEMBL2392136 | 0.57 | CYP2B6 (0.59) | CYP2B6KCNH2SIGMAR1OPRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810047-A | (R) synthetic method of the chiral intermediate of -3- Phenylpiperidine or/and (S) -3- Phenylpiperidine and Ni Lapani | 上海博邦医药科技有限公司 | 2019-05-28 | — | — | CN | disclosed |