Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278177 | 0.91 | THRB (0.46) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL9475470 | 0.89 | TSHR (0.56) | TSHRTHRBAPEX1POLBHTT | |
| SCHEMBL21402156 | 0.85 | TSHR (0.61) | TSHRTHRBAPEX1POLBHTT | |
| SCHEMBL14988989 | 0.84 | TSHR (0.45) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL27984822 | 0.83 | TSHR (0.54) | TSHRTHRBAPEX1POLBHTT | |
| SCHEMBL1260104 | 0.82 | TSHR (0.47) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| Water SCHEMBL4961524 | 0.82 | CHRM5 (0.63) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL5673775 | 0.81 | TSHR (0.50) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL1260812 | 0.81 | TSHR (0.50) | TSHRCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL2022215 | 0.81 | CHRM5 (0.41) | TSHRCHRM5CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110051886-A | The medical device and method that antithrombotic generates | 柯惠有限合伙公司 | 2019-07-26 | — | — | CN | claimed |
| CN-105744965-B | Antithrombotic medical devices and methods | 柯惠有限合伙公司 | 2019-07-09 | — | — | CN | claimed |
| CN-110051886-A | The medical device and method that antithrombotic generates | 柯惠有限合伙公司 | 2019-07-26 | — | — | CN | disclosed |
| CN-105744965-B | Antithrombotic medical devices and methods | 柯惠有限合伙公司 | 2019-07-09 | — | — | CN | disclosed |