Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.96 |
| ▸ | HPGD | P15428 | 6/20 | 0.96 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.96 |
| ▸ | TSHR | P16473 | 4/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.96 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.96 |
| ▸ | RAB9A | P51151 | 2/20 | 0.96 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.96 |
| ▸ | CASP1 | P29466 | 1/20 | 0.96 |
| ▸ | CASP7 | P55210 | 1/20 | 0.96 |
| ▸ | ATM | Q13315 | 1/20 | 0.96 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531544 | 0.98 | HSD17B10 (1.00) | HSD17B10HPGDL3MBTL1TSHRCYP3A4 | |
| SCHEMBL99213 | 0.98 | HSD17B10 (1.00) | HSD17B10HPGDL3MBTL1TSHRCYP3A4 | |
| SCHEMBL29382459 | 0.98 | HSD17B10 (1.00) | HSD17B10HPGDL3MBTL1TSHRCYP3A4 | |
| SCHEMBL29403351 | 0.98 | HSD17B10 (1.00) | HSD17B10HPGDL3MBTL1TSHRCYP3A4 | |
| Acetone SCHEMBL4624685 | 0.88 | HPGD (0.81) | HSD17B10HPGDL3MBTL1TSHRCYP3A4 | |
| SCHEMBL10519360 | 0.85 | HSD17B10 (0.76) | HSD17B10HPGDL3MBTL1TSHRCYP3A4 | |
| SCHEMBL15412953 | 0.84 | HSD17B10 (0.76) | HSD17B10HPGDL3MBTL1TSHRCYP3A4 | |
| SCHEMBL8781298 | 0.84 | HSD17B10 (0.73) | HSD17B10HPGDL3MBTL1TSHRCYP3A4 | |
| SCHEMBL28537289 | 0.83 | HSD17B10 (0.73) | HSD17B10HPGDL3MBTL1TSHRCYP3A4 | |
| SCHEMBL7612163 | 0.83 | HSD17B10 (0.73) | HSD17B10HPGDL3MBTL1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100285995-A1 | Identification and Characterization of Pregnancy-Associated Genetic Signatures and Use Thereof for Diagnosis and Treatment of Breast Cancer | FOX CHASE CANCER CENTER | 2010-11-11 | — | — | US | disclosed |
| WO-2009089102-A2 | IDENTIFICATION AND CHARACTERIZATION OF PREGNANCY- ASSOCIATED GENETIC SIGNATURES AND USE THEREOF FOR DIAGNOSIS AND TREATMENT OF BREAST CANCER | FOX CHASE CANCER CENTER (US) | 2009-07-16 | — | — | WO | disclosed |