Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.81 |
| ▸ | TSHR | P16473 | 3/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | CASP1 | P29466 | 1/20 | 0.81 |
| ▸ | CASP7 | P55210 | 1/20 | 0.81 |
| ▸ | ATM | Q13315 | 1/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382459 | 0.90 | HSD17B10 (1.00) | HPGDL3MBTL1TSHRRAB9AHSD17B10 | |
| SCHEMBL99213 | 0.90 | HSD17B10 (1.00) | HPGDL3MBTL1TSHRRAB9AHSD17B10 | |
| SCHEMBL29531544 | 0.90 | HSD17B10 (1.00) | HPGDL3MBTL1TSHRRAB9AHSD17B10 | |
| SCHEMBL29403351 | 0.90 | HSD17B10 (1.00) | HPGDL3MBTL1TSHRRAB9AHSD17B10 | |
| SCHEMBL2887419 | 0.88 | HSD17B10 (0.96) | HPGDL3MBTL1TSHRRAB9AHSD17B10 | |
| SCHEMBL10519360 | 0.79 | HSD17B10 (0.76) | HPGDL3MBTL1TSHRRAB9AHSD17B10 | |
| SCHEMBL7935821 | 0.78 | HPGD (0.58) | HPGDL3MBTL1TSHRRAB9AHSD17B10 | |
| SCHEMBL15412953 | 0.78 | HSD17B10 (0.76) | HPGDL3MBTL1TSHRRAB9AHSD17B10 | |
| Chrysene SCHEMBL28443586 | 0.78 | HPRT1 (0.70) | HPGDTSHRHSD17B10MAPK1HIF1A | |
| SCHEMBL8781298 | 0.77 | HSD17B10 (0.73) | HPGDL3MBTL1TSHRRAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392334-B1 | THERAPEUTIC METHODS USING HERBAL COMPOSITIONS | GLOBAL CANCER STRATEGIES LTD (CA) | 2008-06-11 | — | — | EP | disclosed |
| US-20050025841-A1 | Therapeutic methods using herbal compositions | GLOBAL CANCER STRATEGIES LTD. (CA) | 2005-02-03 | — | — | US | disclosed |
| EP-1392334-A2 | THERAPEUTIC METHODS USING HERBAL COMPOSITIONS | Global Cancer Strategies Ltd. (CA) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002067961-A2 | THERAPEUTIC USES OF HERBAL COMPOSITIONS | GLOBAL CANCER STRATEGIES LTD. (CA) | 2002-09-06 | — | — | WO | disclosed |