Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581307 | 0.91 | HDAC1 (0.59) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| Octanedioate SCHEMBL29058741 | 0.89 | HDAC8 (0.61) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| Hydroxyamine SCHEMBL27559058 | 0.88 | HDAC1 (0.56) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| Azelaic Acid SCHEMBL11861583 | 0.86 | HDAC3 (0.63) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| Sebacic Acid SCHEMBL3091757 | 0.86 | HDAC3 (0.63) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| Benzoic Acid Hydrazide SCHEMBL15794721 | 0.86 | HDAC3 (0.63) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| Octanedioate SCHEMBL11860281 | 0.86 | HDAC3 (0.63) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL4929881 | 0.85 | HDAC1 (0.76) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL7263142 | 0.85 | HDAC1 (0.52) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| Benzoic Acid Hydrazide SCHEMBL11870297 | 0.84 | HDAC3 (0.60) | HDAC1HDAC8HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368531-B | Improved recombinant production method | 豪夫迈·罗氏有限公司 | 2022-03-25 | — | — | CN | disclosed |