Octanedioate

Octanedioate

SCHEMBL11860281

NNC(=O)c1ccccc1.NNC(=O)c1ccccc1.O=C(O)CCCCCCC(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.63
HDAC4 P56524 4/20 0.63
HDAC1 Q13547 4/20 0.63
HDAC7 Q8WUI4 4/20 0.63
HDAC2 Q92769 4/20 0.63
HDAC10 Q969S8 4/20 0.63
HDAC11 Q96DB2 4/20 0.63
HDAC8 Q9BY41 4/20 0.63
HDAC6 Q9UBN7 4/20 0.63
HDAC9 Q9UKV0 4/20 0.63
HDAC5 Q9UQL6 4/20 0.63
MAPK1 P28482 1/20 0.58
MAPT P10636 4/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
LMNA P02545 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
NPSR1 Q6W5P4 1/20 0.51
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid Hydrazide SCHEMBL15794721 1.00 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
Azelaic Acid SCHEMBL11861583 1.00 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
Sebacic Acid SCHEMBL3091757 1.00 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
Benzoic Acid Hydrazide SCHEMBL11870297 0.98 HDAC3 (0.60) HDAC3HDAC4HDAC1HDAC7HDAC2
Benzoic Acid Hydrazide SCHEMBL11859930 0.94 HDAC3 (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
Benzoic Acid Hydrazide SCHEMBL423791 0.90 NR4A2 (0.59) HDAC3HDAC1HDAC7HDAC2HDAC8
Pimelic Acid SCHEMBL28874757 0.86 HDAC1 (0.66) HDAC3HDAC4HDAC1HDAC7HDAC2
Benzoic Acid Hydrazide SCHEMBL4515671 0.85 CYP3A4 (0.62) HDAC3HDAC1HDAC7HDAC2HDAC8
Benzoic Acid Hydrazide SCHEMBL83514 0.85 CYP3A4 (0.62) HDAC3HDAC1HDAC7HDAC2HDAC8
SCHEMBL20078583 0.85 CYP3A4 (0.62) HDAC3HDAC1HDAC7HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933294-B9 POLYLACTIC ACID RESIN COMPOSITION AND RESIN MOLDED ARTICLE THEREOF DAI-ICHI KOGYO SEIYAKU CO LTD (JP) 2017-08-16 EP disclosed
EP-2933294-B1 POLYLACTIC ACID RESIN COMPOSITION AND RESIN MOLDED ARTICLE THEREOF DAI-ICHI KOGYO SEIYAKU CO LTD (JP) 2017-03-15 EP disclosed
US-9593229-B2 Polylactic acid resin composition and resin molded article thereof DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2017-03-14 US disclosed
EP-2933294-A1 POLYLACTIC ACID RESIN COMPOSITION AND RESIN MOLDED ARTICLE THEREOF Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2015-10-21 EP disclosed
US-20140171559-A1 POLYLACTIC ACID RESIN COMPOSITION AND RESIN MOLDED ARTICLE THEREOF DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2014-06-19 US disclosed
US-3954904-A DICARBOXYLIC ACID DIHYDRAZIDE MITSUBISHI GAS CHEMICAL CO., INC. (JA) 1976-05-04 US disclosed
US-3952072-A MOLDING MATERIALS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1976-04-20 US disclosed