⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14110834 | 0.79 | — | — | |
| SCHEMBL10703438 | 0.73 | — | — | |
| SCHEMBL1264447 | 0.73 | — | — | |
| SCHEMBL10582514 | 0.71 | — | — | |
| SCHEMBL6626494 | 0.70 | CTSK (0.42) | — | |
| SCHEMBL11471565 | 0.68 | — | — | |
| SCHEMBL30223597 | 0.68 | — | — | |
| SCHEMBL9572355 | 0.68 | — | — | |
| SCHEMBL577189 | 0.67 | — | — | |
| SCHEMBL4422184 | 0.67 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115103670-A | Transcription Enhancement Associated Domain (TEAD) transcription factor inhibitors and uses thereof | 达纳-法伯癌症研究所股份有限公司 | 2022-09-23 | — | — | CN | disclosed |