Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 6/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 9/20 | 0.45 |
| ▸ | CDK7 | P50613 | 6/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11971273 | 0.82 | HSD17B10 (0.46) | JAK2PARP1CHEK1CDK7 | |
| SCHEMBL2932210 | 0.82 | KDM4E (0.53) | JAK2PARP1CHEK1CDK7 | |
| SCHEMBL19639885 | 0.80 | JAK2 (0.42) | JAK2PARP1CHEK1CDK7HSP90AA1 | |
| SCHEMBL2927346 | 0.79 | CTSB (0.53) | JAK2 | |
| SCHEMBL9906854 | 0.77 | JAK2 (0.55) | JAK2PARP1CHEK1CDK7HSP90AA1 | |
| SCHEMBL15687275 | 0.76 | CHEK1 (0.64) | CHEK1CDK7 | |
| SCHEMBL4433001 | 0.74 | JAK2 (0.49) | JAK2PARP1CHEK1CDK7HSP90AA1 | |
| SCHEMBL14338764 | 0.74 | HSD17B10 (0.52) | JAK2PARP1CHEK1CDK7FLT3 | |
| SCHEMBL9909105 | 0.74 | JAK2 (0.51) | JAK2CHEK1CDK7HSP90AA1HSP90AB1 | |
| SCHEMBL22711526 | 0.70 | HRH3 (0.71) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003169-A | GPR40 receptor agonist, method for preparing same, and pharmaceutical composition containing same as active ingredient | 株式会社LG化学 | 2019-07-12 | — | — | CN | claimed |
| CN-110003169-A | GPR40 receptor agonist, method for preparing same, and pharmaceutical composition containing same as active ingredient | 株式会社LG化学 | 2019-07-12 | — | — | CN | disclosed |