Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13654269 | 0.86 | MAPT (0.40) | MAPTKDM4EGAARAD52CHRNB4 | |
| SCHEMBL3582361 | 0.81 | CYP11B1 (0.51) | MAPTKDM4EGAARAD52CHRNB4 | |
| SCHEMBL28570739 | 0.79 | CYP11B1 (0.43) | MAPTKDM4EGAARAD52CHRNB4 | |
| SCHEMBL13591314 | 0.78 | NISCH (0.42) | MAPTKDM4EGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL20041209 | 0.77 | CASP3 (0.37) | ALDH1A1HTTCYP11B1CYP11B2 | |
| SCHEMBL28136150 | 0.77 | CYP3A4 (0.44) | CHRNB4CHRNA3CHRNB2CHRNA4MEN1 | |
| SCHEMBL28141259 | 0.77 | MAPT (0.40) | MAPTKDM4EGAARAD52CHRNB4 | |
| SCHEMBL30544452 | 0.77 | MAPT (0.36) | MAPTKDM4EGAARAD52CHRNB4 | |
| SCHEMBL13392140 | 0.74 | TDP1 (0.38) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL19805954 | 0.74 | PARP1 (0.41) | MAPTGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658647-B | The salt of compound | 拜耳医药股份有限公司 | 2019-09-06 | — | — | CN | disclosed |