SCHEMBL28876111

SCHEMBL28876111

O=C(NNC1CCCCNC1)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
EPHX1 P07099 1/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
GAA P10253 1/20 0.50
TSHR P16473 1/20 0.48
EPHX2 P34913 1/20 0.47
HTR2C P28335 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CTSK P43235 1/20 0.44
SGMS2 Q8NHU3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22710505 0.96 ALDH1A1 (0.53) ALDH1A1EPHX1MEN1KMT2AGAA
Hydrochloric Acid SCHEMBL27900667 0.95 ALDH1A1 (0.52) ALDH1A1EPHX1MEN1KMT2AGAA
SCHEMBL28833761 0.91 EPHX1 (0.63) ALDH1A1EPHX1MEN1KMT2AGAA
SCHEMBL3487348 0.91 EPHX1 (0.63) ALDH1A1EPHX1MEN1KMT2AGAA
SCHEMBL21843301 0.87 ALDH1A1 (0.64) ALDH1A1EPHX1MEN1KMT2AGAA
SCHEMBL3295234 0.87 EPHX1 (0.61) ALDH1A1EPHX1MEN1KMT2AGAA
SCHEMBL963963 0.87 EPHX1 (0.61) ALDH1A1EPHX1MEN1KMT2AGAA
SCHEMBL3316063 0.87 EPHX1 (0.61) ALDH1A1EPHX1MEN1KMT2AGAA
SCHEMBL27955816 0.87 ALDH1A1 (0.52) ALDH1A1EPHX1MEN1KMT2AGAA
SCHEMBL2170012 0.86 ALDH1A1 (0.67) ALDH1A1EPHX1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110194770-A Peptide acyl arginine deiminase inhibitor and application thereof 南京药捷安康生物科技有限公司 2019-09-03 CN disclosed