Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400604 | 0.98 | — | — | |
| SCHEMBL3030817 | 0.92 | TBXAS1 (0.56) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL28369782 | 0.90 | TBXAS1 (0.59) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL29386054 | 0.90 | TBXAS1 (0.59) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL6060904 | 0.90 | TBXAS1 (0.59) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL3362078 | 0.85 | — | — | |
| SCHEMBL3431746 | 0.84 | TBXAS1 (0.66) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL9777191 | 0.84 | TBXAS1 (0.60) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL28062565 | 0.82 | TBXAS1 (0.69) | TBXAS1TERTALOX15TAAR1FDPS | |
| SCHEMBL503743 | 0.82 | TBXAS1 (0.69) | TBXAS1TERTALOX15TAAR1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110299527-A | A kind of lithium ion battery negative material and preparation method thereof | 张蓓 | 2019-10-01 | — | — | CN | disclosed |