SCHEMBL28877384

SCHEMBL28877384

CSC(c1cc(O)c(C(=O)O)cc1O)c1cc(O)c(C(=O)O)cc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM1 Q13255 3/20 0.49
MCL1 Q07820 3/20 0.46
CSNK2A1 P68400 1/20 0.46
ALDH1A1 P00352 6/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA12 O43570 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
PTGS2 P35354 2/20 0.39
ALOX5 P09917 1/20 0.39
TSHR P16473 1/20 0.39
KDM4E B2RXH2 5/20 0.37
HPGD P15428 4/20 0.37
HSD17B10 Q99714 4/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
CYP3A4 P08684 2/20 0.37
MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28877484 0.86 ALDH1A1 (0.42) GRM1MCL1CSNK2A1ALDH1A1KDM4E
SCHEMBL20845495 0.78 GRM1 (0.49) GRM1CSNK2A1ALDH1A1CA1CA2
Methyl Alcohol SCHEMBL29088014 0.76 CSNK2A1 (0.56) GRM1MCL1CSNK2A1ALDH1A1CA1
SCHEMBL163610 0.76 CA1 (0.59) MCL1CSNK2A1ALDH1A1CA1CA2
SCHEMBL28877381 0.76 GRM1 (0.47) GRM1MCL1CSNK2A1ALDH1A1CA1
SCHEMBL23796632 0.74 CA12 (0.37) GRM1MCL1CSNK2A1ALDH1A1CA1
SCHEMBL1498023 0.73 CA1 (0.56) MCL1CSNK2A1ALDH1A1CA1CA2
SCHEMBL22206251 0.73 CA1 (0.56) MCL1CSNK2A1ALDH1A1CA1CA2
SCHEMBL596197 0.73 CA1 (0.56) MCL1CSNK2A1ALDH1A1CA1CA2
SCHEMBL3427286 0.73 CA1 (0.56) MCL1CSNK2A1ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115279730-A 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments OM药物公司 2022-11-01 CN claimed
CN-115279730-A 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments OM药物公司 2022-11-01 CN disclosed