Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5389980 | 0.78 | GAA (0.68) | KMT2AMEN1USP2GAAKEAP1 | |
| SCHEMBL30070815 | 0.78 | GAA (0.68) | KMT2AMEN1USP2GAAKEAP1 | |
| SCHEMBL7470787 | 0.77 | KMT2A (0.54) | CA6CA9CA14KMT2AMEN1 | |
| SCHEMBL9729472 | 0.73 | NPC1 (0.47) | KMT2AMEN1LMNAHPGDMAPT | |
| SCHEMBL537488 | 0.72 | MAOB (0.58) | MTORCA3CA6CA5ACA9 | |
| SCHEMBL6850361 | 0.72 | CA3 (0.48) | MTORCA3CA6CA5ACA9 | |
| SCHEMBL30790304 | 0.72 | CA3 (0.48) | MTORCA3CA6CA5ACA9 | |
| SCHEMBL29797486 | 0.72 | MAOB (0.58) | MTORCA3CA6CA5ACA9 | |
| SCHEMBL27031527 | 0.72 | CA3 (0.48) | MTORCA3CA6CA5ACA9 | |
| Methane SCHEMBL27858172 | 0.71 | CA3 (0.46) | MTORCA3CA6CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372571-A | A kind of 2- (2,2- diaryl ethyl)-Cycloamine derivative or salt and synthesis and application and composition | 中国科学院大连化学物理研究所 | 2019-10-25 | — | — | CN | disclosed |