Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MGMT | P16455 | 8/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29973964 | 1.00 | MAPT (0.44) | MAPTRAB9AMEN1NPC1KMT2A | |
| SCHEMBL29974131 | 0.83 | MGMT (0.40) | MAPTRAB9AMEN1NPC1KMT2A | |
| SCHEMBL28877904 | 0.83 | MGMT (0.40) | MAPTRAB9AMEN1NPC1KMT2A | |
| SCHEMBL28957972 | 0.79 | ADORA2A (0.47) | MAPTRAB9AMEN1KMT2AADORA1 | |
| SCHEMBL29974285 | 0.73 | HRH2 (0.42) | MEN1KMT2AMGMTDHFRCCNA2 | |
| SCHEMBL12991933 | 0.69 | MAPT (0.58) | MAPTRAB9AMEN1NPC1KMT2A | |
| SCHEMBL17667876 | 0.68 | ADORA2A (0.54) | MAPTRAB9AMEN1KMT2AADORA1 | |
| SCHEMBL27612801 | 0.68 | PIK3CG (0.53) | MAPTRAB9AMEN1KMT2AADORA1 | |
| SCHEMBL27612725 | 0.68 | CD274 (0.46) | MAPTRAB9ANPC1ADORA1ADORA2A | |
| SCHEMBL9640554 | 0.67 | MGMT (0.49) | MAPTRAB9ANPC1KMT2AMGMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141202-A | Pyrimidopyrazinone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-04 | — | — | CN | disclosed |