Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 8/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955746 | 0.86 | MGMT (0.44) | MGMTCCNA2CDK2CCNA1MAPT | |
| SCHEMBL9465187 | 0.84 | PKM (0.44) | MGMTCCNA2CDK2CCNA1MAPT | |
| SCHEMBL27500630 | 0.84 | MGMT (0.43) | MGMTCCNA2CDK2CCNA1MAPT | |
| SCHEMBL29484712 | 0.84 | MGMT (0.43) | MGMTCCNA2CDK2CCNA1MAPT | |
| SCHEMBL27689385 | 0.81 | MGMT (0.41) | MGMTCCNA2CDK2CCNA1MAPT | |
| SCHEMBL27930543 | 0.80 | PKM (0.44) | MGMTMAPTPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL257010 | 0.80 | ALDH1A1 (0.38) | MGMTCCNA2CDK2CCNA1MAPT | |
| SCHEMBL28276642 | 0.79 | MGMT (0.38) | MGMTCCNA2CDK2CCNA1MAPT | |
| SCHEMBL28877937 | 0.78 | CCNA2 (0.48) | MGMTCCNA2CDK2CCNA1ALDH1A1 | |
| SCHEMBL29974026 | 0.78 | CCNA2 (0.48) | MGMTCCNA2CDK2CCNA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118356812-A | Ternary polymerization polyamide composite membrane and preparation method and application thereof | 南京工业大学 | 2024-07-19 | — | — | CN | claimed |
| CN-113444048-B | High-energy insensitive energetic compound and preparation method thereof | 哈尔滨工业大学（深圳） | 2022-03-18 | — | — | CN | claimed |
| CN-109354825-B | High-temperature-resistant hot-melt benzoxazine resin and preparation method thereof | BEIJING COMPOSITE MATERIAL Co.,Ltd. (CN) | 2021-06-22 | — | — | CN | claimed |
| CN-109438366-A | 2,4,6- triamido -5- nitro-pyrimidine -1,3- dioxide and perchloric acid the self assembly crystalline material containing energy | 中国工程物理研究院化工材料研究所 | 2019-03-08 | — | — | CN | claimed |
| CN-109354825-A | A kind of heat molten type benzoxazine resin resistant to high temperature and preparation method thereof | 北京玻钢院复合材料有限公司 | 2019-02-19 | — | — | CN | claimed |
| CN-107935940-A | The preparation method of 2,4,6 triamido of energy-containing compound, 5 nitro-pyrimidine, 1,3 dioxide | 中国工程物理研究院化工材料研究所 | 2018-04-20 | — | — | CN | claimed |
| CN-107629055-A | A kind of triamterene compound and preparation method thereof | 湖北美林药业有限公司 | 2018-01-26 | — | — | CN | claimed |
| CN-118356812-A | Ternary polymerization polyamide composite membrane and preparation method and application thereof | 南京工业大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-117946010-A | Continuous synthesis method of 2,4, 6-triamino-5-nitropyrimidine | 南京理工大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-117946010-A | Continuous synthesis method of 2,4, 6-triamino-5-nitropyrimidine | 南京理工大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-117946010-A | Continuous synthesis method of 2,4, 6-triamino-5-nitropyrimidine | 南京理工大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-114409861-A | Low-dielectric ablation-resistant benzoxazine resin and preparation method thereof | 北京玻钢院复合材料有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114250480-A | Reduction method of nitroso-nitro pyrimidine compound | 成都化润药业有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-108314597-A | 2,4,6- triamido -5- nitro-pyrimidine -1,3- dioxide and nitric acid self-assembled crystal and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2018-07-24 | — | — | CN | disclosed |
| CN-107935940-A | The preparation method of 2,4,6 triamido of energy-containing compound, 5 nitro-pyrimidine, 1,3 dioxide | 中国工程物理研究院化工材料研究所 | 2018-04-20 | — | — | CN | disclosed |
| EP-0244360-B1 | SUBSTITUTED PYRIMIDINES | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |
| US-4783468-A | Insecticidal 5-pyrimidine carbonitriles | CIBA-GEIGY CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
| CN-87103168-A | The pyrimidines that replaces | — | 1987-12-16 | — | — | CN | disclosed |
| EP-0244360-A2 | Substituted pyrimidines | CIBA-GEIGY AG (CH) | 1987-11-04 | — | — | EP | disclosed |
| US-4145548-A | Method for the production of 5-nitroso-2,4,6-triaminopyrimidine | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-03-20 | — | — | US | disclosed |