Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 9/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23633173 | 0.90 | LPL (0.36) | FFAR1LPLLIPGIDO1TDO2 | |
| SCHEMBL31394025 | 0.86 | IDO1 (0.39) | FFAR1LPLLIPGROCK1IDO1 | |
| SCHEMBL17113584 | 0.83 | LPL (0.41) | FFAR1LPLLIPGIDO1TDO2 | |
| SCHEMBL23638441 | 0.82 | FFAR1 (0.39) | FFAR1LPLLIPGROCK1IDO1 | |
| SCHEMBL30928610 | 0.82 | IDO1 (0.39) | FFAR1LPLLIPGROCK1IDO1 | |
| SCHEMBL31394882 | 0.81 | LPL (0.43) | FFAR1LPLLIPGIDO1TDO2 | |
| SCHEMBL17437290 | 0.81 | FFAR1 (0.57) | FFAR1LPLLIPGIDO1TDO2 | |
| SCHEMBL30041230 | 0.79 | ESR2 (0.40) | FFAR1LPLLIPGIDO1TDO2 | |
| SCHEMBL17113535 | 0.78 | IRAK4 (0.39) | FFAR1LPLLIPGIDO1TDO2 | |
| SCHEMBL23529729 | 0.78 | SNCA (0.38) | FFAR1LPLLIPGIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206730-A1 | PYRIMIDOPYRAZINE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-10-06 | — | — | WO | disclosed |
| CN-115141202-A | Pyrimidopyrazinone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-04 | — | — | CN | disclosed |