Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618435 | 0.94 | PTPN7 (0.37) | TSHRHMGCR | |
| SCHEMBL7642174 | 0.93 | PTPN7 (0.35) | TSHRTHRBHMGCR | |
| SCHEMBL27988190 | 0.91 | PTPN7 (0.38) | TSHRTHRBHMGCR | |
| SCHEMBL9626095 | 0.91 | PTPN7 (0.38) | TSHRTHRBHMGCR | |
| SCHEMBL9340006 | 0.91 | PTPN7 (0.38) | TSHRTHRBHMGCR | |
| SCHEMBL9626661 | 0.91 | PTPN7 (0.38) | TSHRTHRBHMGCR | |
| SCHEMBL28072019 | 0.91 | PTPN7 (0.38) | TSHRTHRBHMGCR | |
| SCHEMBL16161150 | 0.83 | — | — | |
| SCHEMBL16161156 | 0.83 | — | — | |
| SCHEMBL9618430 | 0.82 | HMGCR (0.37) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110386863-A | The method for being prepared with the reduced form halide that carbon-to-carbon unsaturated bond is reduced | 信越化学工业株式会社 | 2019-10-29 | — | — | CN | disclosed |