Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.38 |
| ▸ | HMGCR | P04035 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626661 | 1.00 | PTPN7 (0.38) | PTPN7HMGCRRECQLTDP1TRPM8 | |
| SCHEMBL9626095 | 1.00 | PTPN7 (0.38) | PTPN7HMGCRRECQLTDP1TRPM8 | |
| SCHEMBL27988190 | 1.00 | PTPN7 (0.38) | PTPN7HMGCRRECQLTDP1TRPM8 | |
| SCHEMBL9340006 | 1.00 | PTPN7 (0.38) | PTPN7HMGCRRECQLTDP1TRPM8 | |
| SCHEMBL7642174 | 0.98 | PTPN7 (0.35) | PTPN7HMGCRRECQLTDP1TRPM8 | |
| SCHEMBL9618435 | 0.94 | PTPN7 (0.37) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL28878327 | 0.91 | TSHR (0.39) | HMGCRTSHRTHRB | |
| SCHEMBL9618431 | 0.86 | HMGCR (0.37) | HMGCRALDH1A1 | |
| SCHEMBL9618430 | 0.86 | HMGCR (0.37) | HMGCRALDH1A1 | |
| SCHEMBL9860189 | 0.85 | LMNA (0.39) | PTPN7HMGCRTSHRTHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104098452-B | ω-halogen-2-alkynes aldehyde, produce its method and use it to produce the method for Z-chain Ene alkynyl base acetic acid esters of conjugation | SHIN-ETSU CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-05-11 | — | — | CN | disclosed |