Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 3/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367386 | 0.79 | CLCN2 (0.36) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL6856839 | 0.72 | PDK1 (0.58) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL15614546 | 0.72 | MAPT (0.51) | KCNQ4KCNQ5ALDH1A1KMT2AMEN1 | |
| SCHEMBL28738831 | 0.72 | PDK1 (0.56) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL292274 | 0.72 | AAK1 (0.39) | KCNQ4KCNQ5ALDH1A1CLCN2 | |
| SCHEMBL30227411 | 0.71 | GRIK1 (0.48) | KCNQ4KCNQ5CLCN2PYGLNPC1 | |
| SCHEMBL14085553 | 0.71 | NPC1 (0.58) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL30227212 | 0.71 | GRIK1 (0.48) | KCNQ4KCNQ5CLCN2PYGLNPC1 | |
| SCHEMBL27398698 | 0.71 | MAPT (0.51) | KCNQ4KCNQ5ALDH1A1KMT2AMEN1 | |
| SCHEMBL3789950 | 0.71 | CA12 (0.48) | PDK1PDK2PDK3PDK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325184-A | Amide derivatives | 第一三共株式会社 | 2019-10-11 | — | — | CN | disclosed |